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This means Ligandrol works in a similar way to testosterone and anabolic steroids, although SARMs typically have fewer side effects(but also longer life spans). It's also quite similar to IGF-1, a potent growth hormone secreted by the cells that build muscle. It's generally thought the same chemical as the amino acid glycine, but I'll get into that in a minute.Ligandrol works like IGF-1, as it increases and/or increases the release of testosterone into muscle. But by itself it doesn't increase the size of the IGF-1, it raises its affinity for it in addition to its size (that's what makes it an "antigen" in the body. As it raises this affinity for the IGF-1, it increases the size of the IGF-1, which raises testosterone levels and more, and so forth). Ligandrol does this to other IGF-1, so it has a wide range of effects on IGF-1-dependent tissues (fat, for example).As for its longevity, it seems to have no apparent effect on sperm quality, although in people with IGFBP, its effects seems to have been linked with sperm motility (although the mechanism has yet to be confirmed). It's also said to increase sperm levels, which could lead to fertility.There is, however, evidence that it increases the size of IGF-1-dependent cells in one study (although not enough to cause a noticeable effect on sperm function). So this is another reason why Ligandrol needs to be taken with certain supplements.It's also thought to have negative effects on other IGF-1, but this is unclear. It's very well documented there is a wide range of IGF-1-dependent cells, and that not everybody will have the ability to respond to it the same way.One of the reasons I took Ligandrol before testosterone was because of its potential to increase IGF-1-dependent IGF-1 production in the body. It was thought that IGF-1 could increase IGF-1's affinity for the same amino acid, glycine (by doing this, it would increase it's affinity, which could increase its size). In the case of Ligandrol, this didn't seem to happen. A study in 2012 showed that in this particular group, Ligandrol and testosterone only increased IGF-1-dependent IGF-1 levels within the body, which is not what one might expect from increased IGF-1 production. But it's possible that this is likely just a very specific situation because we know IGF-1 production is increased in response to exercise, and exercise also Similar articles: